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肾为清除水溶性药物的主要器官。为了能合理用药,必须对肾脏处理药物的有关问题有充分了解。此外,了解各种药物对肾功能的影响亦是重要的,从而可使药物性肾损害减少至最低的程度。本文主要谈三个问题。药物对肾脏的作用药物可通过下列几方面影响肾脏。一、药物可作为半抗原而引起免疫反应,从而损害肾脏,此时无论肾小球抑或肾小管都会受到影响。典型的例子有:甲氧苯青霉素(methicillin)引起的抗肾小球基底膜和抗肾小
Kidney is the main organ for removing water-soluble drugs. In order to be able to use medicine properly, you must have a good understanding of the related issues of the kidneys handling drugs. In addition, it is also important to understand the effects of various drugs on renal function, thereby minimizing drug-induced renal damage. This article mainly talks about three issues. Drugs on the role of the kidney Drugs can affect the kidneys through the following aspects. First, the drug can be used as a hapten and cause immune response, thus damaging the kidneys, this time regardless of glomerular or tubular will be affected. Typical examples are: methicillin-induced anti-glomerular basement membrane and anti-renal