论文部分内容阅读
目的:探讨手足口病患儿9种呼吸道病原体免疫球蛋白M(IgM)抗体的阳性情况及临床意义。方法:选择2015年7月至2016年6月于东莞市人民医院住院的0~5岁1151例手足口病患儿为第1组,同时选择0~5岁2298呼吸道感染的住院患儿为第2组,第3组为>5岁的3801呼吸道感染的住院病人。采用间接免疫荧光法联合检测呼吸道嗜肺军团菌1型(LP1)、肺炎支原体(MP)、Q热立克次体(COX)、肺炎衣原体(Cpn)、腺病毒(ADV)、呼吸道合胞病毒(RSV)、甲型流感病毒(IFA)、乙型流感病毒(IFB)、副流感病毒(PIV)9种病原体IgM。结果:第1组LP1、MP、COX、ADV、IFA、IFB、PIV阳性率都比第2组、第3组高,且比总体阳性率高。结论:手足口病患儿常易合并呼吸道病原体感染,应引起临床的重视。
Objective: To investigate the positive and clinical significance of 9 respiratory pathogens immunoglobulin M (IgM) antibodies in children with hand-foot-mouth disease. Methods: From January 2015 to June 2016, 1151 HFMD children aged 0-5 years who were hospitalized in Dongguan People’s Hospital were enrolled as group 1. Children hospitalized with 2298 respiratory infections aged 0-5 years were selected as 2 groups, and group 3 was inpatient with 3801 respiratory infections> 5 years of age. Indirect immunofluorescence assay was used to detect respiratory tract LP1, MP, QX, Cpn, ADV, respiratory syncytial virus (RSV), Influenza A virus (IFA), Influenza B virus (IFB) and parainfluenza virus (PIV). Results: The positive rates of LP1, MP, COX, ADV, IFA, IFB and PIV in group 1 were higher than those in group 2 and group 3, respectively, and higher than the overall positive rate. Conclusion: Children with hand-foot-mouth disease are often complicated by respiratory pathogens, which should arouse clinical attention.