利福平为抗生素类药 ,对结核杆菌具有高度抗菌活性 ,对革兰氏阳性菌、阴性菌均有明显的抗菌作用 ,对麻风杆菌和病毒亦有一定作用。《中国药典》( 1995年版 )采用薄层色谱 -分光光度法测定其含量 ,操作较繁琐。本文采用反相高效液相色谱法测定其含量 ,并与药典法比较 ,结果令人 Rifampin is an antibiotic drug that has a high degree of antibacterial activity against Mycobacterium tuberculosis, a clear antibacterial effect on Gram-positive bacteria and Negative bacteria, and also has a certain effect on Leprosy and viruses. “Chinese Pharmacopoeia” (1995 edition) using thin-layer chromatography - spectrophotometric determination of its content, the operation more cumbersome. In this paper, reversed-phase high performance liquid chromatography determination of its content, and compared with the pharmacopoeial method, the result was