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一些非胰岛素依赖型糖尿病(NIDDM)病人开始时用口服降糖药的疗效满意,但10年后往往仅约50%的病人仍有效。这些病人需改用或加用胰岛素治疗,作者对各种胰岛素疗法作了比较。方法作者将153例病人分成5组:①晨NPH 组:在口服降糖药的基础上,晨7时注射低精蛋白锌胰岛素(NPH 胰岛素);②晚 NPH 组:口服降糖药加晚9时注 NPH 胰岛素;③每日2次胰岛素注射组:NPH 胰岛素和普通胰岛素以7:
Some patients with non-insulin-dependent diabetes mellitus (NIDDM) initially reported satisfactory efficacy with oral hypoglycemic agents, but only about 50% of patients tended to be effective after 10 years. These patients need to switch to or add insulin treatment, the authors made a comparison of various insulin therapies. Methods The authors divided 153 patients into 5 groups: ① morning NPH group: on the basis of oral hypoglycemic agents, hypodermic injection of zinc insulin (NPH insulin) at 7 o’clock in the morning; ② late NPH group: oral hypoglycemic agents plus late 9 When the injection of NPH insulin; 3 times a day insulin injection group: NPH insulin and normal insulin to 7: