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卵巢恶性生殖细胞肿瘤(GCT)并不常见,但在年轻女性中是最常见的生殖系统恶性肿瘤。在敏感化疗使用之前,预后极差,而且大多做了不必要的去势手术。资料表明,大部分GCT在就诊时为Ia期,并且对VAC、VBP、BEP等方案有较好的疗效。提出对Ia期年轻女性应以保留生育机能手术代替根治手术。尽管近年对GCT的治疗有重要性突破,但希望能有多中心研究以发现更好的诊断及治疗方法,进一步改善其预后。
Ovarian malignant germ cell tumors (GCT) are uncommon but are the most common malignant tumors of the reproductive system in young women. Before the use of sensitive chemotherapy, the prognosis is poor, and most do unnecessary castrate surgery. Data show that most of the GCT in the treatment of Ia period, and VAC, VBP, BEP and other programs have a good effect. Proposed young women in stage Ia should be replaced by fertility surgery instead of radical surgery. Despite the important breakthroughs in the treatment of GCT in recent years, it is hoped that there will be a multicentre study to find better diagnosis and treatment to further improve its prognosis.