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目的对老年Ⅰ～Ⅱ级高血压病(60例)和非老年Ⅰ～Ⅱ级高血压病(60例)应用培哚普利(雅施达)治疗并进行比较。方法120例高血压病患者均服用培哚普利;老年组:2～4mg;非老年组:4～8mg;1次/d,疗程4周。主要观察两组降压疗效。结果两组在治疗后均有显著的降压效果(P<0.01),但是两组之间的降压总有效率和降压幅度均无明显差异(P>0.05),治疗过程中未发现严重不良反应事件。结论培哚普利治疗老年Ⅰ～Ⅱ级高血压病的疗效较好而且安全
Objective To compare the effects of perindopril on aged patients with type Ⅰ-Ⅱ hypertension (60 cases) and non-elderly patients with type Ⅰ-Ⅱ hypertension (60 cases). Methods 120 patients with hypertension were taking perindopril; elderly group: 2 ~ 4mg; non-elderly group: 4 ~ 8mg; 1 / d, treatment for 4 weeks. The main observation of two groups antihypertensive effect. Results Both groups had significant antihypertensive effect after treatment (P <0.01), but there was no significant difference between the two groups in total effective rate of antihypertensive efficacy and antihypertensive rate (P> 0.05), and no serious treatment was found Adverse reaction events. Conclusion The effect of perindopril in the treatment of elderly patients with grade Ⅰ ~ Ⅱ hypertension is good and safe