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血管肽酶抑制剂是一组抑制神经内肽酶和血管紧张素转换酶 (ACE)的药物 ,作用表现为增强利尿多肽活性和抑制肾素 血管紧张素 醛固酮系统 (RAAS)。因为这种直接作用机制的特点 ,它们有望成为新的一类治疗高血压和慢性心力衰竭的药物。目前有几种该类药物已经进入临床试验阶段。O
Vasopeptidase inhibitors are a group of drugs that inhibit neuroendopeptidase and angiotensin-converting enzyme (ACE), which act to enhance diuretic polypeptide activity and inhibit the renin-angiotensin-aldosterone system (RAAS). Because of this direct mechanism of action, they are expected to become a new class of drugs for treating hypertension and chronic heart failure. There are several such drugs have entered the clinical trial phase. O