唇腭裂常可单独发生或两者并发,但腭裂合并鼻骨缺如畸形罕见。现报告1例。病历:王晓丽,女,5岁。生后发现鼻梁塌陷,哺乳时可见腭部豁裂。因发音不清,要求手术修复腭裂,于1989年8月21日入院。追问其母孕产史,患儿母亲孕期患感冒,并多次口服解热镇痛及磺胺类药物。家族中无先天畸形病史。体检:发育、营养中等,神志清楚,呈腭裂语 Cleft lip and palate can often occur alone or both, but the cleft palate nasal bone missing as deformity rare. Now report 1 case. Medical history: Wang Xiaoli, female, 5 years old. After birth, the bridge of the nose collapses and palatine spondylolysis is seen when breastfeeding. Due to unclear pronunciation, requiring surgery to repair cleft palate, was admitted on August 21, 1989. Asked about her mother's mother's history of pregnancy, mother and child suffering from cold during pregnancy, and repeatedly oral antipyretic analgesic and sulfonamides. No history of congenital malformations in the family. Physical examination: development, moderate nutrition, conscious, was cleft palate