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目的分析2008-2015年重庆市渝北区美沙酮维持治疗(MMT)门诊病人的艾滋病病毒(HIV)感染情况及相关影响因素。方法通过全国艾滋病直报系统,获取2008-2015年重庆市渝北区MMT门诊HIV抗体实际检测的2 871例入组病人的人口学信息、HIV检测等数据,采用SPSS 20.0软件包分析数据。结果 MMT病人HIV新发阳性率从2008年的2.07%下降到2015年的0.07%;不同婚姻状况(P<0.05)、不同吸毒方式(P<0.01)、是否注射毒品(P<0.01)、是否共用针具(P<0.001)、是否感染丙型肝炎病毒(P<0.05)等,HIV抗体阳性检出率的差异均有统计学意义;是否注射毒品(P<0.001)与是否共用针具(P<0.01),对HIV阳性率具有较强的预测作用。结论在2008-2015年重庆市渝北区MMT门诊病人的HIV新发阳性率呈下降趋势,注射毒品与共用针具是预测感染HIV的关键因素。
Objective To analyze the prevalence of HIV infection among methadone maintenance treatment (MMT) outpatients in Yubei district of Chongqing during 2008-2015 and its related factors. Methods The demographic information and HIV testing data of 2 871 patients admitted to MMT clinic in Chongqing Yubei District during 2008-2015 were obtained through the National Direct AIDS Reporting System. The data were analyzed by SPSS 20.0 software package. Results The rate of new HIV positive rate in MMT patients decreased from 2.07% in 2008 to 0.07% in 2015. Whether there was any difference in marital status (P <0.05), different drug use methods (P <0.01), drug injection (P <0.01) (P <0.001), whether infected with hepatitis C virus (P <0.05), the positive detection rate of HIV antibody was statistically significant difference; whether injecting drug (P <0.001) and sharing needle ( P <0.01), the positive rate of HIV has a strong predictive effect. Conclusions In 2008-2015, the rate of new HIV positive cases in MMT outpatients in Yubei District of Chongqing Municipality shows a decreasing trend. Injecting drugs and sharing needles are the key factors in predicting the HIV infection.