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目的:观察90例急性冠脉综合征患者入院后血清肌钙蛋白I(cTnI)、肌红蛋白(Mb)和血清肌酸激酶同工酶(CK-MB)变化,探讨其对心脏事件的近期、远期预报价值。方法:用干化学法消毒针刺指头,取一滴血滴于三合一试纸条加样槽内20分钟观察,新增标志物红线cTnI、Mb、CK-MB为阳性。结果:CK-MB在心电图ST段抬高急性心梗组出现阳性率最高,ST段不抬高急性心梗组次之,不稳定性心绞痛组最低;Mb在ST段抬高组或不抬高急性心梗组阳性率均高,但两者之间差异无显著性cTnI在ST段抬高组与不抬高急性心梗组阳性率均高,但存在差异,不稳定性心绞痛组也有一定阳性率。结论:cTnI测定对判断急性冠脉综合征患者发生心脏事件有重要预报价值。Mb可作为心肌损害早期筛选指标。CK-MB在判断急性心梗方面有肯定价值。
Objective: To observe the changes of serum cTnI, Mb and CK-MB in 90 patients with acute coronary syndrome (ACS) after admission, and to investigate the changes of cTnI, , Long-term forecast value. Methods: Sterilize the finger of the acupuncturing with dry chemical method, take one drop of blood drop to observe the trisomy strip plus sample tank for 20 minutes, add the red line cTnI, Mb and CK-MB of the marker positive. Results: The positive rate of CK-MB in ST-segment elevation acute myocardial infarction group was the highest, followed by ST segment elevation in acute myocardial infarction group and the lowest in unstable angina group. Mb was not elevated in ST-segment elevation group The positive rate of acute myocardial infarction group were high, but no significant difference between the two cTnI in ST-segment elevation group and non-elevated acute myocardial infarction group positive rate, but there are differences, unstable angina also have some positive rate. Conclusion: The cTnI assay has important predictive value in judging the cardiac events in patients with acute coronary syndrome. Mb can be used as an early screening indicator of myocardial damage. CK-MB in the judgment of acute myocardial infarction have a positive value.