论文部分内容阅读
目的:研究分析D-二聚体含量水平与老年男性进展性卒中的相互关系。方法:通过选取我院2013年9月至2014年9月收治的进展性脑卒中老年男性患者48例作为实验组,并选取同一时期的正常体检者48例(对照组),分别检测两组D-二聚体水平含量进行比较,并检测实验组治疗前后的两组D-二聚体水平含量变化。结果:实验组的老年进展性脑卒中组患者D-二聚体水平在1.6±1.37 mg/L,明显高于对照组健康者的D-二聚体含量水平,而且D-二聚体检测值显示为阳性的有41例所占比例为85.4%,对照组测定呈阳性的有7例(14.58%),两组患者在D-二聚体阳性率相互比较,差异显著(P<0.05)。实验组经过30 d治疗后,D-二聚体含量水平明显下降,D-二聚体阳性率也降低了62.48%,治疗前后患者的D-二聚体含量水平及其阳性率相比,显著性差异,具有统计学意义(P<0.05)。结论:在老年男性进展性脑卒中的预测过程中,D-二聚体可以作为分子标志物,对患者体内血栓早期形成具有重要的临床诊断价值。
OBJECTIVE: To study the relationship between D-dimer levels and stroke in elderly men. Methods: Forty-eight elderly male patients with progressive stroke admitted to our hospital from September 2013 to September 2014 were enrolled in this study. Forty-eight healthy subjects (control group) were enrolled in the same period. Two groups of D - dimer levels were compared and the experimental group before and after treatment of two groups D-dimer level changes. Results: The D-dimer level in the elderly stroke group was 1.6 ± 1.37 mg / L, which was significantly higher than that in the control group, and the D-dimer level 41 cases showed positive ratio of 85.4%, 7 cases (14.58%) were positive in the control group, the positive rate of D-dimer in both groups were significantly different from each other (P <0.05). The experimental group after 30 d treatment, D-dimer levels decreased significantly, D-dimer-positive rate also decreased 62.48%, before and after treatment in patients with D-dimer levels and the positive rate was significantly Sex differences, with statistical significance (P <0.05). Conclusion: D-dimer can be used as a molecular marker in the prediction of advanced male stroke. It has important clinical diagnostic value in the early formation of thrombus in the elderly.