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目的:观察布地奈德、硫酸特布他林雾化吸入治疗儿童哮喘的疗效。方法:将100例患者随机分为两组,两组均在综合治疗基础上,治疗组用布地奈德+硫酸特布他林雾化吸入,对照组给予地塞米松、利巴韦林雾化吸入,bid,5～7d为1个疗程。对两组治疗前后的症状、体征持续时间进行疗效观察比较。结果:治疗组的治愈率(68.52%)和总有效率(96.30%)都明显高于对照组的治愈率(26.09%)和总有效率(76.09%),两组间有统计学差异(P<0.01)。在缓解喘憋、缩短咳嗽及肺部啰音持续时间方面治疗组明显优于对照组(P<0.01)。两组均未见明显不良反应。结论:布地奈德和硫酸特布他林联合雾化吸入治疗儿童哮喘疗效明显,安全方便。
Objective: To observe the curative effect of budesonide and terbutaline sulphate inhalation on childhood asthma. Methods: 100 patients were randomly divided into two groups. On the basis of comprehensive treatment, the two groups were treated with budesonide and terbutaline sulphate inhalation. The control group was given dexamethasone and ribavirin Inhalation, bid, 5 ~ 7d for a course of treatment. On the two groups before and after treatment of symptoms and signs of the duration of treatment were observed and compared. Results: The cure rate (68.52%) and total effective rate (96.30%) of the treatment group were significantly higher than that of the control group (26.09%) and the total effective rate (76.09%), the difference was statistically significant (P <0.01). The treatment group was significantly better than the control group (P <0.01) in relieving wheezing, shortening the duration of cough and pulmonary rales. No obvious adverse reactions were found in both groups. Conclusion: Budesonide and terbutaline sulphate combined with inhalation of asthma in children is effective and safe.