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作者观察了60例急性重症病毒性肝炎。将全部病例分为两个组,Ⅰ组30例用强的松龙和溶菌酶。Ⅱ组30例只用强的松龙。强的松龙每日40毫克,持续治疗4周。溶菌酶每日2次。每次300毫克,肌注,持续治疗10天。此外有时加服多种维生素和野蔷薇的糖浆或冲剂,而没用其它药物。强的松龙和溶菌酶联合治疗比强的松龙单独治疗有更大的疗效。在联合治疗下,乏力、消化不良消失,食欲恢复及黄疸减轻(原胆红素含量Ⅰ组为8.5±0.7毫克％,Ⅱ组为7.9±0.3％毫克。经过治疗10天,胆红素降低到Ⅰ组4.0±0.4毫克％,Ⅱ组5.8±0.3毫克％)两组胆红素测定结果表明:Ⅰ组比Ⅱ组胆红素下降的更快些。在Ⅰ组一般不需辅助治疗措施,而Ⅱ组有3例由于中毒症状和黄疸的加重,在治疗
The authors observed 60 cases of acute severe viral hepatitis. All cases were divided into two groups, 30 cases of group Ⅰ with prednisolone and lysozyme. Group Ⅱ 30 patients with prednisolone only. Prednisolone 40 mg daily for 4 weeks. Lysozyme 2 times a day. Each 300 mg, intramuscular injection, continuous treatment for 10 days. In addition, sometimes plus a variety of vitamins and bromeliad syrup or granules, and no other drugs. Combination therapy of prednisolone and lysozyme has a greater effect than the treatment of prednisolone alone. Under the combined treatment, fatigue, indigestion, loss of appetite, and jaundice were reduced (the original bilirubin content was 8.5 ± 0.7 mg in group I and 7.9 ± 0.3% mg in group II. After 10 days of treatment, the bilirubin was reduced to Ⅰ group 4.0 ± 0.4 mg%, Ⅱ group 5.8 ± 0.3 mg%) bilirubin test results showed that: Ⅰ group than in group b bilirubin decreased faster. In group I generally do not need adjuvant therapy, while group Ⅱ in 3 patients due to symptoms of poisoning and jaundice aggravated in the treatment