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鉴于子宫出血与子宫内膜前列腺素(PGs)含量过高或各种PGs之间的比例失调关系密切,近年来,有些人尝试将PG合成酶抑制剂用于子宫出血患者,取得了减少出血量30—50％的效果,提示该病的出血机制似与PGs的含量和比例变化有关。对于子宫内膜的PGF_(2α)和PGE_2的含量,曾有学者进行过研究。随着对PG代谢的研究和深入,花生四稀酸的代谢产物前列腺环素(PGI_2)和血环素A_2(TXA_2)在维持正常血液凝固性中的作用日趋受到重视,前者是目前所知最强的血小板聚集抑制和血管扩张剂,后者则
In view of uterine bleeding and endometrial prostaglandin (PGs) content is too high or a variety of PGs imbalance between the close, in recent years, some people try PG synthetase inhibitors in patients with uterine bleeding, achieved a reduction in bleeding 30-50% of the effect, suggesting that the bleeding mechanism of the disease seems to PGs content and the proportion of changes. For the endometrial PGF_ (2α) and PGE_2 content, have been studied by scholars. With the research of PG metabolism, PGI_2 and TXA_2, the metabolites of arachidonic acid, are gaining more and more attention in maintaining normal blood coagulation. The former is the most known Strong platelet aggregation inhibition and vasodilators, the latter