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４例经手术及病理证实的颅内原发性弥漫性恶性肿瘤，其中１例为脑膜胶质瘤病，３例为脑膜肉瘤病。病理特点表现为肿瘤细胞沿蛛网膜下腔广泛播散，阻塞脑底池，而无明显的瘤结节。病人临床症状和体征似急性或亚急性脑膜炎，脑积水是常见的合并症。鉴别诊断应注意与细菌或霉菌性脑膜炎及癌性脑膜病相区别。确诊要依靠脑组织活检及脑脊液细胞学检查。化疗、放疗加脑脊液分流是此类肿瘤主要治疗方法。预后不良。
4 cases of primary intracranial diffuse malignant tumor confirmed by operation and pathology, of which 1 case was gliomatosis and 3 cases were meningiomatosis. Pathological features of the tumor cells spread widely along the subarachnoid space, obstruction of the brain pool, and no obvious tumor nodules. Patients with clinical symptoms and signs of acute or subacute meningitis, hydrocephalus is a common complication. Differential diagnosis should be noted with the bacterial or fungal meningitis and cancerous meningitis phase difference. Diagnosis depends on brain tissue biopsy and cerebrospinal fluid cytology. Chemotherapy, radiotherapy and cerebrospinal fluid shunt is the main treatment of such tumors. Poor prognosis.