论文部分内容阅读
目的观察联合运用奥美拉唑、西沙比利治疗胃食管反流病(GERD)的疗效。方法将GERD 80例,于清晨空腹服用奥美拉唑20 mg/次,2次/d;西沙比利10 mg/次,3次/d;疗程8周,治疗前及治疗结束后,再行胃镜检查,观察记录食管炎及反流症状的改善程度。结果症状评价,显效42例,有效30例,总有效率94.7%。胃镜评价:除外4例非糜烂性反流性食管炎(NERD)外,76例中显效42例,有效31例,总有效率96.1%。结论奥美拉唑及西沙比利治疗GERD有较好的疗效,可作为GERD的常规治疗方案供临床使用。
Objective To observe the curative effect of omeprazole and cisapride in the treatment of gastroesophageal reflux disease (GERD). Methods Eighty patients with GERD were treated with omeprazole 20 mg twice daily in fasting morning and twice daily with cisapride 10 mg once daily for 8 weeks. Before and after treatment, Gastroscopy, observation and recording of esophagitis and reflux symptoms improvement. Results Symptom evaluation, effective in 42 cases, effective in 30 cases, the total effective rate 94.7%. Gastroscopy evaluation: Excluding 4 cases of non-erosive reflux esophagitis (NERD), 76 cases markedly effective in 42 cases, effective in 31 cases, the total effective rate was 96.1%. Conclusion Omeprazole and cisapride in the treatment of GERD has a good curative effect and can be used as a routine treatment of GERD for clinical use.