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目的探讨乳腺叶状囊肉瘤的临床特点、外科治疗方法及影响预后的因素。方法对24例乳腺叶状囊肉瘤患者采用局部切除11例,单侧乳房切除术10例,乳房切除并腋窝淋巴结清除3例,其中5例(20%)曾诊断为乳腺腺纤维瘤或巨纤维瘤因术后肿瘤复发而经历2~3次局部切除术。结果术后病检证实:低度恶性11例,中度恶性9例,高度恶性4例。随访1~10年(平均5.2年),局部复发率29.1%,5年生存率97%。结论乳腺叶状囊肉瘤发病率低,易误诊;手术切除是其首选的治疗方法,局部切除术后复发应行乳房切除;多数乳腺叶状囊肉瘤恶性程度较低,进展缓慢,预后较好;乳腺叶状囊肉瘤预后与肿瘤的病理类型、肿瘤大小和手术切除是否彻底有关。
Objective To investigate the clinical characteristics, surgical treatment and prognostic factors of breast cystosarcoma of breast. Methods Twenty-four patients with cystosarcoma of the breast were treated with partial resection in 11 cases, unilateral mastectomy in 10 cases, mastectomy and axillary lymph node dissection in 3 cases, of which 5 cases (20%) had been diagnosed as breast gland fibroids or giant fibroids Tumors undergo postoperative tumor recurrence and experience 2 to 3 times local excision. Results Postoperative pathological examination confirmed: 11 cases of low grade, 9 cases of moderately malignant, 4 cases of highly malignant. Follow-up 1 to 10 years (mean 5.2 years), local recurrence rate of 29.1%, 5-year survival rate of 97%. Conclusions The incidence of cystosarcoma in breast is low and easily misdiagnosed. Surgical resection is the first choice for its treatment. Breast resection should be performed after partial resection. Most cystosarcoma of breast has lower malignancy, slow progress and better prognosis. Prostate cystosarcoma prognosis and tumor pathological types, tumor size and surgical excision is completely related.