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目的探析将甲氨蝶呤配合用于腹腔镜输卵管切开术来治疗输卵管妊娠时的临床治疗效果。方法在输卵管妊娠患者中随机抽取80例,随机分为观察组和对照组。40例对照组患者单纯采用腹腔镜输卵管切开术进行治疗;40例观察组患者则将甲氨蝶呤配合应用于腹腔镜输卵管切开术进行治疗。观察并比较二组患者的治疗效果。结果观察组患者的输卵管病灶消失时间为(5.0±2.1)d,远少于对照组的(7.3±3.9)d;观察组患者的持续性输卵管妊娠(PEP)发生比率为2.50%,对照组为17.50%;观察组明显低于对照组;观察组患者的血hCG恢复时间也要明显短于对照组;二组比较差异具有统计学意义(P<0.05)。结论在对输卵管妊娠患者进行腹腔镜下的输卵管切开术时配合应用甲氨蝶呤可有效改善手术治疗效果,减低患者PEP的发生比率,值得推广应用。
Objective To investigate the clinical effect of methotrexate combined with laparoscopic tubal incision in the treatment of tubal pregnancy. Methods Totally 80 cases of tubal pregnancy were randomly divided into observation group and control group. Forty patients in the control group were treated with laparoscopic tubal incision alone. Forty patients in the observation group were treated with methotrexate for laparoscopic tubal incision. Observed and compared the treatment effect of two groups of patients. Results The disappearance time of tubal lesions in the observation group was (5.0 ± 2.1) days, much lower than that in the control group (7.3 ± 3.9 days). The incidence of persistent tubal pregnancy (PEP) in the observation group was 2.50% 17.50% respectively. The observation group was significantly lower than the control group. The recovery time of blood hCG in the observation group was shorter than that of the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion In the tubal pregnancy patients undergoing laparoscopic tubal surgery with methotrexate can effectively improve the surgical treatment effect and reduce the incidence of PEP in patients, it is worth promoting the application.