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对22例子宫肌瘤患者应用放射免疫法测定血清雌二醇（E2）、孕酮（P）、睾酮（T）、促卵泡素（FSH）、促黄体生成素（LH）、垂体生乳素（PRL）6种激素的含量；同时应用SP免疫组化法对肌瘤组织的石蜡切片进行雌激素受体（ER）、孕激素受体（PR）含量测定；并与正常子宫平滑肌组织进行对照。结果：肌瘤组血清P、T、PRL含量显著高于对照组（P＜0．01），肌瘤组织中ER显著高于正常子宫平滑肌组织（P＜0．05），PR亦较正常子宫平滑肌组织高。提示子宫肌瘤的发生与血清雌、孕激素水平增高或子宫局部ER、PR含量增加有关。
Serum estradiol (E2), progesterone (P), testosterone (T), follicle stimulating hormone (FSH), luteinizing hormone (LH), pituitary prolactin (PRL) were measured by radioimmunoassay in 22 patients with uterine fibroids. Meanwhile, SP immunohistochemistry method was used to detect the content of estrogen receptor (ER) and progesterone receptor (PR) in paraffin sections of myoma tissue, and compared with the normal uterine smooth muscle. Results: The levels of P, T and PRL in fibroids group were significantly higher than those in control group (P <0.01). The ER in fibroid tissues was significantly higher than that in normal uterine smooth muscle tissues (P <0.05) Smooth muscle tissue high. Tip uterine fibroids and serum estrogen and progesterone levels increased or uterine local ER, PR content increased.