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目的研究蛋白支持疗法对妊娠期肾病综合征患者的治疗效果及对妊娠结局的影响。方法选择2013年4月-2016年3月医院妇产科收治妊娠期肾病综合征患者300例随机分为观察组和对照组各150例,观察组患者采用控制血压和补充人血白蛋白的方法给予治疗,而对照组仅以控制血压的方法给予治疗,比较两组患者在治疗过程中的效果及并发症等妊娠结局情况。结果治疗后,观察组在24h尿蛋白、血清总蛋白、白蛋白等均有明显提高,而对照组却相应有所下降,观察组新生儿出生体重高于对照组,两组比较差异均有统计学意义(P<0.05)。结论蛋白支持疗法在妊娠期肾病综合征治疗中能够有效地改善患者的肾功能,并且对胎儿的发育有着非常重要的作用。
Objective To study the therapeutic effect of protein support therapy on patients with gestational nephrotic syndrome and its effect on pregnancy outcome. Methods From April 2013 to March 2016, 300 patients with pregnancy-induced nephrotic syndrome admitted to the department of obstetrics and gynecology in our hospital were randomly divided into observation group (150 cases) and control group (150 cases). Patients in observation group were treated with blood pressure control and human serum albumin supplementation While the control group only given blood pressure control treatment, the two groups of patients in the treatment of the effect and complications such as pregnancy outcome. Results After treatment, the urinary protein, serum total protein and albumin in the observation group were significantly increased in the observation group compared with the control group, but the birth weight in the observation group was higher than that in the control group, with statistical differences between the two groups Significance (P <0.05). Conclusion Protein support therapy can effectively improve renal function in patients with nephrotic syndrome during pregnancy, and plays a very important role in the development of the fetus.