作者共使用8株麻风菌(6株是由未经治疗的瘤型麻风病人在小鼠中的传代菌株,2株是直接从病人接种于小鼠者)。感染菌量为5.0×10~3和1.0×10~4。治疗组每个菌株接种15只小鼠,并用20只小鼠作为不治疗的对照组。利福平在饲料中的含量分别为0.01、0.003、0.001、0.0003％。测定最小抑菌剂量时,除SBL_(16282)菌株在接种后75天给药外,均从感染之日起连续给药。当对照组小鼠每足垫菌数 The authors used a total of eight leprosy strains (6 were passaged strains of mice from untreated leprosy patients and 2 were inoculated directly into the mice from patients). Infected bacteria were 5.0 × 10 ~ 3 and 1.0 × 10 ~ 4. Each strain of the treated group was inoculated with 15 mice and 20 mice were used as untreated control. Rifampicin in the feed content were 0.01,0.003,0.001,0.0003%. Determination of the minimum inhibitory dose, except for SBL_ (16282) strains administered 75 days after inoculation, were administered continuously from the date of infection. When the control group mice per litter number