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目的探讨磷酸铝凝胶(洁维乐)联合葡萄糖酸锌片治疗婴幼儿急性非细菌性腹泻的临床疗效。方法选取2013—2014年广州市妇女儿童医疗中心收治的婴幼儿急性非细菌性腹泻患儿120例,按随机数字表法分为洁维乐组(A组),蒙脱石散剂组(B组),洁维乐加锌组(C组),各40例。A组患儿予以洁维乐治疗,B组患儿予以蒙脱石散剂治疗,C组患儿予以洁维乐联合葡萄糖酸锌片治疗。观察3组患儿临床疗效及不良反应发生情况。结果A组患儿总有效率高于B组,C组患儿总有效率高于A、B组,差异有统计学意义(P<0.05);3组患儿均未发生严重不良反应。结论洁维乐联合葡萄糖酸锌片治疗婴幼儿急性非细菌性腹泻的临床疗效显著,且不良反应少。
Objective To investigate the clinical efficacy of aluminum phosphate gel (Jievi Le) combined with zinc gluconate in the treatment of acute non-bacterial diarrhea in infants. Methods A total of 120 infants with acute non-bacterial diarrhea admitted to Guangzhou Women’s and Children’s Medical Center from 2013 to 2014 were selected and divided into three groups according to the random number table: group A (group A), group B (group B) ), Jie Weile plus zinc group (C group), each 40 cases. A group of children to be Jieweile treatment, B group of children treated with montmorillonite powder, C group of children with Jieweile combined with zinc gluconate treatment. The clinical efficacy and adverse reactions in 3 groups were observed. Results The total effective rate of children in group A was higher than that of group B, and the total effective rate of children in group C was higher than that of group A and B (P <0.05). No serious adverse reactions occurred in the three groups. Conclusion Jieveil combined with zinc gluconate tablets in the treatment of acute non-bacterial diarrhea in infants and young children clinical efficacy was significant, and adverse reactions.