癌症是长期不明原因发热的常见病因,但是甲状腺癌引起发热尚无报道。本文报道1例胸骨后甲状腺肿发生未分化癌表现长期发热,并对常用显象技术未能检查出肿瘤进行讨论。 患者女,66岁,干咳3周就诊。既往病史自幼有胸骨后甲状腺肿。体检时有发热,可触及结节性甲状腺肿延续至胸骨后间隙,无压痛,余未见异常。实验室检查异常的包括:红细胞沉降率100mm/h,血红蛋白10g/dl,白细胞增多,为15000/mm~3,中性90%。甲状腺机能检查结果正常。胸部X线片显示胸骨后甲状腺肿。胸部计算机断层(CT)扫 Cancer is a common cause of long-term unexplained fever, but no reports of fever caused by thyroid cancer. This article reports a case of undifferentiated breast sternal goiter showed long-term fever, and the commonly used imaging techniques failed to detect the tumor were discussed. Female patient, 66 years old, dry cough 3 weeks treatment. Past history of a retrosternal goiter. Physical examination when fever, nodular goiter can reach the back of the space after the sternum, no tenderness, I did not see abnormalities. Laboratory abnormalities include: erythrocyte sedimentation rate 100mm / h, hemoglobin 10g / dl, leukocytosis, 15000 / mm ~ 3, 90% neutral. Thyroid function test results normal. Chest X-ray showed a retrosternal goiter. Chest computed tomography (CT) scan