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对Ⅱ型糖尿病患者血清载脂蛋白ＡＩ和Ｂ的评估山西省人民医院（０３００１２）张效春，李建夫，杨蕴华，荣秀芹载脂蛋白（Ａｐｏ）是血浆脂蛋白的蛋白部分，国内有报告ＡｐｏＡＩ／ＡｐｏＢ比值是糖尿病（ＤＭ）并冠心病（ＣＨＤ）、动脉粥样硬化（ＡＳ）的一项重要危险预报因子。就此我们对Ⅱ型糖尿病病入的血脂及载脂蛋白ＡＩ与Ｂ做了测定与比较，以便找出糖尿病脂代谢紊乱的早期发现指标。对象与方法一、对象：①对照组：取婚检、体检健康人５０例，均无高血压、内分泌及肝肾疾病，心电图、空腹及餐后血糖均正常。②糖尿病组：取住院及门诊按ＷＨＯ诊断标准为Ⅱ型ＤＭ者７０例。均采用口服降山西职工医学院糖药（优降糖、达美康和降糖灵）治疗。二、测定方法：①全部受检对象均于禁食１２小时后次晨采静脉血，分别测定总胆固醇（ＴＣ）、高密度脂蛋白（ＨＤＬ－Ｃ）、甘油三脂（ＴＧ）、ＡｐｏＡＩ和ＡｐｏＢ。②ＡｐｏＡＩ及ＡｐｏＢ测定采用联合免疫电泳法。试剂盒由上海中医学院武进新乐生化试剂厂提供（ＡｐｏＡＩ、ＡｐｏＢｌ００联合免疫试剂盒）。③ＴＣ、ＨＤＬ－Ｃ和ＴＧ均采用酶法。结果各次测定结果见附表。ＤＭ组和对照组比较ＴＣ、ＨＤＬ－Ｃ和ＡｐｏＡＩ无显著性差异（Ｐ＞０．０５）
Evaluation of Serum Apolipoprotein AI and B in Patients with Type 2 Diabetes Mellitus Apo is a protein component of plasma lipoprotein. ApoAI / ApoB ratio is an important predictor of diabetes (DM) and coronary heart disease (CHD) and atherosclerosis (AS). In this connection, we measured the levels of lipids and apolipoproteins AI and B in patients with type II diabetes in order to find out the early detection indicators of diabetic lipid metabolism disorder. Subjects and methods First, the object: ① control group: take premarital examination, physical examination 50 healthy people, no hypertension, endocrine and liver and kidney disease, electrocardiogram, fasting and postprandial blood glucose were normal. ② Diabetes group: Inpatients and outpatients according to WHO diagnostic criteria for Type II DM in 70 cases. Both oral administration of Shanxi Medical College sugar (glyburide, Deltamethrin and hypoglycemic) treatment. Second, the determination of methods: ① all subjects were fasting 12 hours after the morning of the morning pumping venous blood, were measured total cholesterol (TC), high density lipoprotein (HDL-C), triglyceride (TG), ApoAI and ApoB. ② ApoAI and ApoB assay using a combination of immunoelectrophoresis. The kit was supplied by Wujin Xinle Biochemical Reagent Factory of Shanghai Traditional Chinese Medicine Institute (ApoAI, ApoBl00 Co-immunization kit). ③ TC, HDL-C and TG are enzymatic. Results of the results of the test table. There was no significant difference in TC, HDL-C and ApoAI between DM group and control group (P> 0.05)