论文部分内容阅读
目的探讨婴儿癫癎与TORCH感染之间的关系。方法采用ELISA法对40例婴儿癫癎患儿(癫癎组)和30例同龄健康婴儿(健康对照组)进行血清弓形虫(TOX)、风疹病毒(RV)、巨细胞病毒(CMV)和单纯疱疹病毒(HSVⅠ-、HSVⅡ-)抗体IgM、IgG水平检测。结果癫癎组TORCH-IgM抗体阳性7例,其中CMV-IgM阳性7例,TOX-IgM、RV-IgM、HSVⅠ--IgM和HSVⅡ--IgM阳性例数均为0,健康对照组TORCH-IgM抗体阳性例数为0,癫癎组CMV-IgM检出阳性率高于健康对照组(P<0.05),其他TORCH系列抗体的检出阳性率与健康对照组比较差异无统计学意义(Pa>0.05)。≤6个月癫癎患儿CMV-IgG抗体阳性24例(82.76%),7~12个月的癫癎患儿CMV-IgG抗体阳性5例(45.45%),≤6个月癫癎患儿CMV-IgG抗体阳性率高于7~12个月患儿(P<0.05)。≤6个月癫癎患儿CMV-IgM抗体阳性6例(20.69%),7~12个月的癫癎患儿CMV-IgM抗体阳性1例(9.09%),≤6个月和7~12个月癫癎患儿CMV-IgM抗体检出阳性率比较差异无统计学意义(P>0.05)。结论婴儿癫癎与CMV感染有一定关系。
Objective To investigate the relationship between infant epilepsy and TORCH infection. Methods 40 cases of infantile epilepsy (epilepsy group) and 30 healthy infants (healthy control group) were enrolled in this study. Serum Toxoplasma gondii (TOX), rubella virus (RV), cytomegalovirus (CMV) Herpes virus (HSV Ⅰ -, HSV Ⅱ -) antibody IgM, IgG levels were detected. Results The positive cases of TORCH-IgM in epilepsy group were positive in 7 cases, CMV-IgM positive in 7 cases, TOX-IgM, RV-IgM, HSVⅠ-IgM and HSVⅡ- The positive rate of CMV-IgM in the epilepsy group was higher than that in the healthy control group (P <0.05). The positive rate of other TORCH antibodies was not significantly different from the healthy control group (Pa> 0.05). 24 (82.76%) were positive for CMV-IgG antibodies in children with epilepsy ≤ 6 months, 5 (45.45%) were positive for CMV-IgG antibodies in children with epilepsy at 7-12 months, and those with epilepsy ≤ 6 months The positive rate of CMV-IgG antibody was higher than that in children aged 7-12 months (P <0.05). 6 (20.69%) were positive for CMV-IgM antibody in children with epilepsy ≤6 months, 1 case (9.09%) were positive for CMV-IgM antibody in children with epilepsy at 7 ~ 12 months, ≤6 months and 7-12 The positive rate of CMV-IgM antibody in children with epilepsy was no significant difference (P> 0.05). Conclusion There is a certain relationship between infantile epilepsy and CMV infection.