近一个世纪来,继 Metchnikoff 的重要发现之后,人们对 Mφ在免疫反应中的地位已经有了明确的认识。现已认识到,Mφ几乎参与了整个免疫反应,有人称之为机体的三大免疫活性细胞之一。Mφ不仅参与机体的特异性免疫反应和非特异性免疫反应,同时也是这两种免疫的“桥梁细胞”。它不仅参与免疫反应的输入臂,而且也参与免疫反应的输出臂,是一种十分活跃的效应细胞。尤其近年来,Mφ的抗肿瘤作用日 For nearly a century, following the important findings of Metchnikoff, there is a clear understanding of the role of Mφ in the immune response. It has been recognized that Mφ is involved in almost the entire immune response, which some call the body’s three major immune-competent cells. Mφ not only involved in the body’s specific immune response and non-specific immune response, but also the two immune “bridge cells.” It is not only involved in the immune response of the input arm, but also involved in the immune response of the output arm, is a very active effector cells. Especially in recent years, anti-tumor effect of Mφ day