流行性出血热病毒主要在肾、脑和肺等组织检出,近年来,也有报告可在肝脏组织中检出。1987年前后,国内外相续报告了流行性出血热累及肝脏的临床病例,但有关肝脏受累的病理改变报告甚少,超微结构尚无报告。本文观察了9例临床确诊为流行性出血热患者的肝穿刺标本。9例患者均有肝脏受累的临床表现和血清酶学检查。标本采取在发病的第13—27天之间,均为恢复期。 Epidemic hemorrhagic fever virus is mainly detected in the tissues of kidney, brain and lung, and in recent years, it has also been reported in liver tissues. Before and after 1987, clinical reports of epidemic hemorrhagic fever involving the liver were reported in succession, but little is reported about the pathological changes of hepatic involvement, and there is no report on the ultrastructure. This article observed 9 cases of clinically diagnosed patients with epidemic hemorrhagic liver puncture specimens. All 9 patients had clinical manifestations of liver involvement and serum enzyme tests. Specimens taken in the incidence of the first 13-27 days, are recovery period.