论文部分内容阅读
慢性δ肝炎的诊断依据通常是血清中存在高滴度抗δ总抗体(抗-HD)和/或肝细胞中存在δ抗原(HDAg)。IgM 抗-HD 可在部分急性δ病毒(HDV)感染期病人中短暂出现,并已成为慢性感染的一项敏感标志。作者测定了一组抗-HD 阳性慢性肝病病人的抗体和肝内 HDAg,并研究了这两项标志与肝损害的程度和严重性的关系。共观察36例 HBsAg 阳性及组织学证实为慢性肝病和高滴度抗-HD 抗体(>1∶
The diagnosis of chronic hepatitis delta is usually based on the presence of high titers of anti-delta total antibody (anti-HD) in serum and / or the presence of delta antigens (HDAg) in hepatocytes. IgM anti-HD may transiently occur in some patients with acute deltavirus (HDV) infection and has become a sensitive marker of chronic infection. The authors measured the antibody and intrahepatic HDAg in a panel of patients with anti-HD positive chronic liver disease and examined the relationship between these two markers and the extent and severity of liver damage. A total of 36 cases of HBsAg positive and histologically confirmed as chronic liver disease and high-titer anti-HD antibody (> 1: