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目的：研究脑血宁口服液对大鼠局灶性脑缺血损伤的保护作用。方法：通过阻断大鼠一侧大脑中动脉（ ＭＣＡ） 造成局灶性脑缺血模型（ＭＣＡＯ），观察脑血宁口服液对神经病学症状、被动性条件反射、脑梗死面积及脑组织病理组织学的影响。结果：脑血宁口服液可显著改善模型大鼠神经病学症状，缩小梗塞面积，促进坏死灶内血管和胶质细胞增生修复，减少脑组织水肿和炎性细胞浸润。结论：脑血宁口服液对大鼠局灶性脑缺血具有明显的防治作用。
Objective: To study the protective effect of Naoxining oral liquid on focal cerebral ischemic injury in rats. METHODS: The cerebral ischemia model (MCAO) was induced by blocking the middle cerebral artery (MCA) of the rat and the neurological symptoms, passive conditioned reflex, cerebral infarct size, and brain histopathology were observed in Naoxining oral solution. Histological influence. RESULTS: Naoxining oral solution can significantly improve the neurological symptoms of model rats, reduce the infarct size, promote the repair of blood vessel and glial cell proliferation in necrotic foci, and reduce brain tissue edema and inflammatory cell infiltration. Conclusion: Naoxining oral liquid has obvious preventive and therapeutic effects on focal cerebral ischemia in rats.