目的:探讨半夏泻心汤联合埃索美拉唑治疗慢性萎缩性胃炎的效果。方法:随机将我院2016年2月~2017年2月收治的70例慢性萎缩性胃炎患者分为两组,每组35例。对照组行常规西医治疗,观察组在对照组的基础上给予半夏泻心汤治疗。比较两组临床疗效。结果:治疗后,观察组总有效率、Hp阳性率及胃泌素水平等指标均明显优于对照组,差异具有统计学意义(P<0.05)。两组均未发生明显不良反应。结论:半夏泻心汤联合埃索美拉唑治疗慢性萎缩性胃炎效果显著,能够有效改善临床症状,提高了患者的生活质量,安全性高,值得临床中推广应用。 Objective: To investigate the effect of Banxiaxiexin Decoction combined with esomeprazole in the treatment of chronic atrophic gastritis. Methods: Seventy patients with chronic atrophic gastritis who were admitted to our hospital from February 2016 to February 2017 were randomly divided into two groups (n = 35 in each group). Control group routine Western medicine treatment, the observation group was given on the basis of the control group Banxiaxiexin Tang treatment. The clinical efficacy of the two groups were compared. Results: After treatment, the total effective rate, the positive rate of Hp and the level of gastrin in the observation group were significantly better than those in the control group, with statistical significance (P <0.05). No significant adverse reactions occurred in both groups. Conclusion: Banxiaxiexin Decoction combined with esomeprazole is effective in treating chronic atrophic gastritis, which can effectively improve clinical symptoms and improve the quality of life of patients with high safety. It is worth popularizing and applying in clinic.