黑色素瘤发源于中枢神经系统极为少见。我院收治经手术及病理证实的神经系肿瘤中,有脑及脊髓黑色素瘤各一例,占中枢神经系统肿瘤3‰。 Winkel 认为诊断的标准是1.肿瘤在软脑膜上弥散生长。2.须有长期随访观察或包括尸检确实排除中枢神经系统以外的病灶。3.未作过其他器官黑色素瘤切除术。本文报告两例在病理上证实为黑色素瘤,体查未发现皮肤眼球脉络膜及内脏黑色素瘤的证据,手术时黑色素瘤沿软脑膜向四周蔓延,脑膜及脊膜有黑色素斑。脑部黑色素瘤术为91天死亡于脑出血,脊髓 Melanoma originating in the central nervous system is extremely rare. In our hospital, there was one case of melanoma of the brain and spinal cord, accounting for 3 ‰ of the central nervous system tumors. According to Winkel, the standard of diagnosis is 1. The tumor grows diffusely on the pia mater. 2. Must have long-term follow-up observation or include autopsy does exclude other than the central nervous system lesions. No other organ melanoma resection. This article reports two cases of pathologically confirmed melanoma, physical examination did not find evidence of skin eye choroid and visceral melanoma, meningioma surgery along the four week spread around the meninglate and meningitis meningitis. Brain melanoma surgery for 91 days died of cerebral hemorrhage, spinal cord