自拟培元定喘方联合卡介菌多糖核酸注射液腧穴注射治疗支气管哮喘的临床观察

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目的:观察支气管哮喘的治疗过程中运用卡介菌多糖核酸注射液腧穴注射与自拟培元定喘方联合治疗的临床疗效,为中西医结合运用于支气管哮喘的治疗提供理论依据。方法:探究对象选择2013年7月~2015年7月于我院治疗的120例支气管哮喘患者,随机均分为观察组与对照组,对照组采用常规西药治疗,观察组卡介菌多糖核酸注射液腧穴注射与自拟培元定喘方联合治疗,比较两组患者临床疗效,治疗前后肺功能、哮喘控制测试(ACT)评分以及血清免疫球蛋白水平。结果:观察组临床控制总有效率为91.67%显著高于对照组(71.67%),有统计学意义(P<0.05);观察组治疗后FEV1、FEV1/FVC均显著高于对照组,有统计学意义(P<0.05),观察组治疗后ACT评分与对照组差异显著,有统计学意义(P<0.05);观察组治疗后IgE与对照组差异显著(P<0.05),IgA、IgG、IgM无显著性差异,无统计学意义(P>0.05)。结论:运用卡介菌多糖核酸注射液腧穴注射与自拟培元定喘方联合治疗支气管哮喘能显著提高临床疗效,控制临床症状的同时肺功能得到明显的恢复,通过卡介菌多糖核酸注射液腧穴注射降低IgE水平能够缓解支气管哮喘症状。 OBJECTIVE: To observe the clinical curative effect of combination therapy of BCG polysaccharide nucleic acid injection with acupoints injected with self-prepared Peiyuan Dingchuan prescription in the course of the treatment of bronchial asthma, and to provide a theoretical basis for the treatment of bronchial asthma by combining traditional Chinese and western medicine. Methods: Subjects were selected from 120 patients with bronchial asthma who were treated in our hospital from July 2013 to July 2015. The patients were randomly divided into observation group and control group. The control group was treated with conventional western medicine. The observation group was injected with BCG- The acupoint injection combined with Peiyuan Dingchuan recipe were used to compare the clinical curative effect, pulmonary function, asthma control test (ACT) score and serum immunoglobulin level before and after treatment. Results: The total effective rate of clinical observation in observation group was 91.67%, which was significantly higher than that in control group (71.67%) (P <0.05). The FEV1 and FEV1 / FVC in observation group were significantly higher than those in control group (P <0.05). The ACT score of the observation group after treatment was significantly different from that of the control group (P <0.05). There was a significant difference between the observation group and the control group (P <0.05) IgM no significant difference, no statistical significance (P> 0.05). Conclusion: The combination of BCG polysaccharide nucleic acid injection acupoints and self-Peiyuan Dingchuan Fang combined treatment of bronchial asthma can significantly improve clinical efficacy, control of clinical symptoms at the same time lung function was significantly restored through the BCG polysaccharide nucleic acid injection Acupoint injection to reduce the level of IgE can alleviate the symptoms of bronchial asthma.
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