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我院自1991年3月至1992年11月底共收治特发性突发性感音神经性耳聋(突聋)80例,随机分成治疗组和对照组。治疗组40例,44耳,经蝮蛇抗栓酶治疗,治愈率47.7%,有效率81.8%。对照组40例,48耳,经用低分子右旋糖酐、丹参、病毒唑等药物综合治疗,治愈率25%,有效率50%,治愈率及有效率,治疗组明显高于对照组,经统计学处理,有显著性差异(P<0.05,P<0.01)。据血液流变学资料分析,治疗组治疗后全血低切粘度,高切粘度等五个指标明显下降。研究表明,蝮蛇抗栓酶治疗突聋,疗效高,无明显毒副作用,为治疗突聋开辟了新途径。
Our hospital from March 1991 to the end of November 1992 were treated 80 cases of idiopathic sudden sensorineural deafness (sudden deafness), were randomly divided into treatment group and control group. Treatment group 40 cases, 44 ears, the viper antithrombin treatment, the cure rate was 47.7%, the effective rate of 81.8%. The control group of 40 cases, 48 ears, the use of low molecular weight dextran, Salvia, ribavirin and other drugs comprehensive treatment, the cure rate was 25%, the effective rate of 50%, the cure rate and efficiency, the treatment group was significantly higher than the control group, Treatment, there was a significant difference (P <0.05, P <0.01). According to hemorheology data analysis, the treatment group after treatment, low blood viscosity, high shear viscosity and other five indicators decreased significantly. Studies have shown that viper antithrombotic treatment of sudden deafness, high efficacy, no obvious side effects, for the treatment of sudden deaf opened up new avenues.