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目的观察中晚期宫颈癌患者术前介入化疗对宫颈癌的辅助治疗效果,探讨临床应用价值。方法本院73例IIb-IV期宫颈癌患者在术前予以动脉插管化疗及栓塞治疗,有宫颈癌根治术适应证者接受手术治疗,分析治疗效果。结果 73例宫颈癌介入化疗总有效率78.1%;疗程结束后,65例(89.0%)接受手术治疗,8例(11.0%)改为全程放疗;介入化疗过程中,54例患者有不同程度的消化道反应,31例患者出现骨髓抑制;5年生存率82.2%。结论宫颈癌介入化疗对缩小癌灶有一定效果,介入化疗后联合放疗及手术治疗,5年生存率可达80%以上。
Objective To observe the effect of adjuvant chemotherapy for cervical cancer in advanced cervical cancer patients and to explore the clinical value. Methods 73 cases of stage IIb-IV cervical cancer patients undergoing arterial catheterization chemotherapy and embolization before surgery, with cervical cancer indications for surgical treatment, analysis of treatment. Results The total effective rate of interventional chemotherapy in 73 cases of cervical cancer was 78.1%. After the treatment, 65 cases (89.0%) were treated by surgery and 8 cases (11.0%) were treated by full course radiotherapy. During the interventional chemotherapy, 54 patients had different degrees of Gastrointestinal reactions, bone marrow suppression occurred in 31 patients; 5-year survival rate was 82.2%. Conclusion Interventional chemotherapy for cervical cancer has some effect on shrinking the foci of cancer. After combined chemotherapy and radiotherapy and surgery, the 5-year survival rate can reach more than 80%.