在临床和法庭毒物学领域,广泛范围药物筛选是一项非常重要而又常被忽视的工作。这项工作的侧重点是所有毒物学相关的物质,无论其结构或极性如何,都能被分离、检测和鉴定。近几年来,我们已尝试建立一个系统的固相提取方法,能够有效地从生物检材中分离出药物,并已经建立了利用单根Bond—Elut Certify固相柱提取的步骤。虽然这个步骤适用 In the field of clinical and forensic toxicology, a wide range of drug screening is a very important and often overlooked task. The focus of this work is that all toxicologically relevant substances, regardless of their structure or polarity, can be separated, detected and identified. In recent years we have attempted to establish a systematic solid-phase extraction method that can effectively separate drugs from biological samples and have established a procedure for extraction using a single Bond-Elut Certify solid-phase column. Although this step applies