论文部分内容阅读
目的：探讨心肌钙蛋白Ⅰ（ＣＴｎＩ）定量测定在监测心力衰竭患者病情进展方面的应用价值。方法：采用微粒子化学发光法定量检测血ＣＴｎＩ。结果：３７例确诊为心力衰竭、心功能Ⅳ级患者比２６例非心血管病对照组患者ＣＴｎＩ明显升高（Ｐ＜０００１），而两组同时检测的磷酸肌酸激酶同工酶（ＣＫ－ＭＢ）浓度无明显差异（Ｐ＝０９２）。心衰组的ＣＴｎＩ浓度随病情好转而降至正常范围，病情恶化患者ＣＴｎＩ持续不降或继续上升。结论：血ＣＴｎＩ定量测定对心衰病情监测及预后估计有一定应用价值。
Objective: To investigate the value of quantitative detection of cardiac troponin Ⅰ (CTnI) in monitoring the progression of heart failure patients. Methods: Quantitative detection of blood CTnI by microparticle chemiluminescence method. Results: The CTnI of 37 patients diagnosed with heart failure and heart function Ⅳ grade was significantly higher than that of 26 non-cardiovascular control patients (P <0001), while the two groups of simultaneous detection of creatine phosphokinase CK-MB) concentration was no significant difference (P = 092). In patients with heart failure, the CTnI concentration dropped to the normal range as the condition improved. The CTnI in patients with worsening condition continued to decrease or continued to rise. Conclusion: Quantitative determination of blood CTnI has certain value in the monitoring and prognosis of heart failure.