15例严重慢性中性白细胞减少症患者随访8～31(平均15)年的资料。除1例外均为女性。2例在青春期发病,3例超过60岁,平均年龄41岁。病人的家庭成员中,没有患过中性白细胞减少症或反复感染。10例最初白细胞计数为2,000～2,500个/mm~3,2例为4,000个/mm~3以上,平均2,300个/mm~3。最初中性白细胞绝对计数有9例少于250个/mm~3,全部患者均 Fifteen patients with severe chronic neutropenia were followed up for 8 to 31 (mean 15) years. All but one were female. 2 cases of onset in adolescence, 3 cases over 60 years old, average age 41 years old. The patient’s family members, have not had neutropenia or recurrent infections. The initial white blood cell counts in 10 patients ranged from 2,000 to 2,500 per mm3, with 2 in 4 cases over 3,000 per mm3. The initial absolute neutrophil count 9 cases less than 250 / mm ~ 3, all patients were