论文部分内容阅读
骨髓外浆细胞肉瘤是一种少见的恶性肿瘤,鼻腔为好发部位。我们对20例原发于鼻腔的浆细胞肉瘤患者进行临床与病理分析。本瘤多发生于中老年龄组,男多于女。临床上表现为鼻塞,涕中带血,鼻内肿物,触之易出血,常发生浸润与转移。病理组织学表现为,肿瘤由单一不同分化的浆细胞组成,瘤细胞破坏原有的组织结构,瘤细胞异型性明显,排列密集,弥漫浸润。间质稀少,常有淀粉样物质沉积。本文20例鼻腔浆细胞肉瘤的组织学类型与生物学行为间有一定的内在联系,随着瘤细胞分化低,肿瘤分级高,其侵犯邻近组织,淋巴结及其它器官转移,并发骨髓瘤病及其死亡率均增高。
Extramedullary plasma cell sarcoma is a rare malignant tumor, nasal cavity as a predilection site. We performed a clinical and pathological analysis of 20 patients with plasma cell sarcoma that originated in the nasal cavity. The tumor occurred in the middle-aged group, more men than women. Clinically manifested as stuffy nose, tears in the blood, nasal tumor, easy to touch the bleeding, often infiltration and metastasis. Histopathological findings, the tumor consists of a single differentiated plasma cells, tumor cells destroy the original organizational structure, tumor atypia obvious, arranged in dense, diffuse infiltration. Interstitial sparse, often amyloid deposition. In this paper, 20 cases of nasal plasma cell sarcoma histological types and biological behavior have some intrinsic relationship between, with the tumor cell differentiation is low, the tumor grade high, its invasion of adjacent tissues, lymph nodes and other organ metastases, complicated with myeloma and its Mortality increased.