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应用原位末端标记法（ＴＵＮＥＬ）及免疫组化技术对３２例胃低分化腺癌石蜡包埋组织切片进行检测，结果发现，胃癌组织中有细胞凋亡和ＢｃＬ－２蛋白的表达，二者阳性率分别为８１．２５％和６８．７５％，ＢｃＬ－２表达越明显的区域，细胞凋亡越少。实验结果提示，ＢｃＬ－２蛋白可能通过抑制细胞凋亡而参与胃癌的发生与发展。
TUNEL and immunohistochemistry were used to detect the paraffin-embedded tissues of 32 poorly differentiated adenocarcinomas. The results showed that there were apoptosis and BcL-2 protein expression in gastric cancer tissues. The positive rates were 81.25% and 68.75%, respectively. The more obvious the expression of BcL-2, the less apoptosis. The experimental results suggest that BcL-2 protein may participate in the occurrence and development of gastric cancer by inhibiting apoptosis.