作者报告了1例,有16年糖尿病病史的63岁女病人,于非心原性肺水肿发作后2个月,呈持续性的呼吸功能不全,经肺针刺活检,呈现局灶性肺纤维化,并有一些上皮样细胞肉芽肿,但无坏死倾向。虽经类固醇激素试验治疗,没有明显改善。患者于19年前曾患过结节病,此次发病后,一度有细菌感染的征象,故作者认为,本例ARDS之发生,除了感染和结节病可能起一定作用外,长期糖尿病导致的肺毛细血管通透 The authors report a case of a 63-year-old woman with a 16-year history of diabetes who presented with persistent respiratory insufficiency 2 months after onset of non-cardiogenic pulmonary edema. A needle-aspirated biopsy showed focal lung fibrosis And there are some epithelioid cell granulomas but no necrosis tendency. Although steroid hormone test treatment, no significant improvement. The patient had had sarcoidosis 19 years ago. After the onset of the disease, there was a history of bacterial infection. Therefore, in this case, the occurrence of ARDS may be caused by long-term diabetes in addition to infection and sarcoidosis Pulmonary capillary permeability