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目的:观察压敏胶贴剂舒筋贴的活血化瘀、抗炎作用。方法:观察舒筋贴对大鼠急性血瘀模型全血黏度、血浆黏度的影响;采用大鼠肉芽肿试验、蛋清致大鼠足肿胀试验、二甲苯致小鼠耳肿胀试验,考察受试药物的抗炎作用。结果:舒筋贴可显著降低大鼠急性血瘀模型全血黏度和血浆黏度;能明显抑制大鼠肉芽肿的增生;可降低蛋清致大鼠足跖肿胀度;抑制二甲苯引起的小鼠耳廓炎性肿胀。结论:舒筋贴具较强的活血化瘀及抗炎作用。
Objective: To observe the effect of pressure sensitive adhesive patch Shujin Tie on blood circulation and anti-inflammatory. Methods: The effect of Shujin Tie on the whole blood viscosity and plasma viscosity in acute blood stasis model of rats was observed. Granuloma test in rat, foot swelling test induced by egg white and ear swelling test in mice induced by xylene were conducted. Anti-inflammatory effect. Results: Shufugai can significantly reduce the whole blood viscosity and plasma viscosity of acute blood stasis model rats; can significantly inhibit the proliferation of rat granuloma; can reduce egg white induced rat paw swelling; inhibition of xylene-induced mouse ear Inflammatory swelling. Conclusion: Shujin paste with strong blood circulation and anti-inflammatory effects.