糖尿病病人施行手术后有5～10％伤口发生不同程度的愈合不良,特别是易发生感染。糖尿病病人比非糖尿病病人的清洁伤口易于感染,经常变成慢性而难以愈合的溃疡,尤其在肢体部分。本文回顾糖尿病的现代概念,复习近80年来外科治疗成功和失败的经验,研究糖尿病动物模型的伤口愈合情况,以及考虑手术前后控制糖尿病的临床意义。糖尿病实际上是一个征候群,而不是一个 Diabetic patients after surgery 5 to 10% of the wounds to varying degrees of healing, especially prone to infection. Diabetic patients are more susceptible to cleaning wounds than nondiabetic patients and often become chronic and difficult to heal ulcers, especially in the limbs. This article reviews the modern concept of diabetes, reviewing the experience of successful and unsuccessful surgical procedures in nearly 80 years, studying the wound healing in diabetic animal models, and considering the clinical implications of controlling diabetes before and after surgery. Diabetes is actually a syndrome, not one