论文部分内容阅读
目的探讨不稳定型心绞痛(UP)阿托伐他汀强化降脂治疗对血脂及hs-CRP水平的影响。方法本院收治108例UP患者,分为阿托伐他汀强化治疗组和常规治疗组,分别于入院12h内给予阿托伐他汀40mg/d和20mg/d,连续使用4周。结果阿托伐他汀强化治疗组治疗4周时血浆中TC、TG、LDL-C及hs-CRP水平均显著低于阿托伐他汀常规治疗组,两组治疗后血脂水平比较无统计学差异(P>O.05),hs-CRP水平比较有统计学差异(P<0.05)。结论阿托伐他汀强化治疗明显减轻UP患者冠状动脉粥样斑块的炎症反应,明显降低血脂水平。
Objective To investigate the effect of atorvastatin on lipid lowering and hs-CRP levels in patients with unstable angina pectoris (UP). Methods A total of 108 patients with UP were enrolled in this study. Patients were divided into atorvastatin intensive treatment group and conventional treatment group. Atorvastatin 40 mg / d and 20 mg / d were given within 12 hours of admission, respectively, for 4 weeks. Results The levels of TC, TG, LDL-C and hs-CRP in atorvastatin-treated group were significantly lower than those of atorvastatin 4 weeks after treatment. There was no significant difference in blood lipid levels between the two groups P> 0.05), hs-CRP levels were statistically significant (P <0.05). Conclusions Atorvastatin treatment significantly attenuates the inflammatory response of atherosclerotic plaques in UP patients and significantly reduces the level of blood lipid.