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风湿热是一种侵及全身各组织器官,尤其是心脏结缔组织的胶原纤维和基质的疾病。其临床重要性在于它可伴发风湿性心脏炎,并可演变为慢性风湿性心脏病(风心病)。风湿热的发病率在大多数发达国家已显著下降,而在发展中国家仍然较高。近年来,我国风湿热发病率有逐渐下降趋势,但仍为严重威胁青壮年健康的常见病,因此积极防治很有必要。自1944年Jones标准发表以来,随着临床、流行病学、细菌学和免疫学等深入研究,对风湿热的认识有若干进展。本文仅对几个有关问题概略介绍。
Rheumatic fever is a disease that invades the collagen fibers and matrix of various tissues and organs throughout the body, especially cardiac connective tissue. Its clinical importance is that it can be associated with rheumatic carditis, and can evolve into chronic rheumatic heart disease (rheumatic heart disease). The incidence of rheumatic fever has dropped significantly in most developed countries and remains high in developing countries. In recent years, the incidence of rheumatic fever in our country has been gradually declining, but it is still a common disease that seriously threatens the health of young adults. Therefore, it is necessary to actively prevent and treat rheumatic fever. Since the Jones standard was published in 1944, with the clinical, epidemiological, bacteriological and immunological in-depth study of rheumatic fever awareness of some progress. This article only a brief overview of a few related issues.