以往的研究表明内淋巴囊的上皮细胞有调节内淋巴的作用,而内淋巴囊吸收内淋巴的过程是需要Na~+-K~+-ATP酶驱动的。Na~+-K~+-ATP酶由α、β两种位于胞浆膜内的亚单位组成,α亚单位有α_1、α_2、α_3三种异构体,它含有包括Na~+-K~+-ATP磷酸化结合位点在内的所有酶催化位点,而β亚单位有β_1、β_2两种异构体,它可能在Na~+-K~+-ATP酶复合体功能成熟及与膜结合方面起作用。Na~+-K~+-ATP酶构形的多样性与其多 Previous studies have shown that endolymphatic sac epithelial cells regulate the role of endolymphatic, and endolymphatic sac to absorb endolymph process is required Na ~ + -K ~ + -ATP enzyme-driven. The Na ~ + -K ~ + -ATPase is composed of α, β subunits located in the cytoplasm. The α subunit contains α_1, α_2 and α_3 isoforms which contain Na ~ + -K ~ + -ATP phosphorylation sites, and the beta subunit has both β 1 and β 2 isoforms, which may be functional Na + -K + -ATP enzyme complex and with Membrane binding plays a role. The diversity of Na ~ + -K ~ + -ATPase conformation is more than that of Na ~ + -K ~ + -ATPase