论文部分内容阅读
目的：探讨小儿慢性腹痛与幽门螺杆菌（HP）感染的关系，为慢性腹痛患儿提供部分病因诊断和治疗的依据。方法：采用血清HP－lgG定量测定或胃内容物及齿槽分泌物PCR基因检测HP－DNA，对185名3岁～14岁慢性上中腹、脐周痛为临床表现患儿进行监测。并随机选出其中32名进行钡透及胃镜对照检查。结果：185名患儿中HP感染占51．9％，并随年龄增长而增高。HP（＋）者100％引起上消化道慢性炎症或溃疡。治论：小儿慢性腹痛与HP感染有密切关系。HP感染→胃炎→溃疡→慢性腹痛是构成小儿中上胶、脐周痛疼的病因链。HP的检测是小儿慢性腹痛病因诊断和治疗首选筛查手段。
Objective: To investigate the relationship between chronic abdominal pain and Helicobacter pylori (HP) infection in children and provide some evidences for the diagnosis and treatment of chronic abdominal pain. Methods: HP-DNA was detected by quantitative analysis of serum HP-lgG or PCR products of gastric contents and alveolar secretions, and 185 children with chronic upper abdomen and umbilical pain at the age of 3 to 14 years old were monitored for clinical manifestations. And randomly selected 32 of them for barium and gastroscopy control examination. Results: HP infection in 185 children accounted for 51.9%, and increased with age. 100% of HP (+) cause chronic upper gastrointestinal inflammation or ulcer. Theory: Children with chronic abdominal pain and HP infection are closely related. HP Infections → Gastritis → Ulcers → Chronic abdominal pain is the causal chain that forms the sore and painful umbilical cord in children. HP’s detection is the preferred screening method for the diagnosis and treatment of pediatric chronic abdominal pain.