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雌激素调节蛋白的发现进一步揭示了雌激素致瘤机制。评价雌激素受体及雌激素调节蛋白在肿瘤生物学行为中的作用，对指导临床应用内分泌治疗有一定意义。本文就它们与胃肠道肿瘤的关系加以综述。
The discovery of estrogen regulatory proteins further reveals estrogen tumorigenicity. Evaluation of the role of estrogen receptor and estrogen regulatory proteins in tumor biological behavior, to guide the clinical application of endocrine therapy has some significance. This article reviews their relationship with gastrointestinal tumors.