The Effect of the Surgical Margins on the Outcome of Patients with Head and Neck Squamous Cell Carci

来源 :Cancer Biology & Medicine | 被引量 : 0次 | 上传用户:fh2019
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Objective To assess the impact of close or positive surgical margins on the outcome,and to determine whether margin status influence the recurrence rate and the overall survival for patients with head and neck cancers. Methods Records from 1996 to 2001 of 413 patients with primary head and neck squamous cell carcinoma(SCC) treated with surgery as the first line treatment were analysed.Of these patients,82 were eligible for the study.Patients were followed up for 5 years. Results Patients with margins between 5-10 mm had 50%recurrence rate(RR),those with surgical margins between 1-5 mm had RR of 59%and those with positive surgical margins had RR of 90%(P=0.004).The 5-year survival rates were 54%,39%and 10%,respectively(P=0.002). Conclusions Unsatisfactory surgical margin is an independent risk factor for recurrence free survival as well as overall survival regardless of the other tumor and patient characteristics. Objective To assess the impact of close or positive surgical margins on the outcome, and to determine whether margin status influence the recurrence rate and the overall survival for patients with head and neck cancers. Methods Records from 1996 to 2001 of 413 patients with primary head and Both squamous cell carcinoma (SCC) treated with surgery as the first line treatment were analysed. Of these patients, 82 were eligible for the study. Patients were followed up for 5 years. Results Patients with margins between 5-10 mm had 50% recurrence rate (RR), those with surgical margins between 1-5 mm had RR of 59% and those with positive surgical margins had RR of 90% (P = 0.004). The 5-year survival rates were 54%, 39% and 10 %, respectively (P = 0.002). Conclusions Unsatisfactory surgical margin is an independent risk factor for recurrence free survival as well as overall survival regardless of the other tumor and patient characteristics.
其他文献
2007年5月26日上午,位于南昌市红谷滩新区凤凰洲片区的经济适用房“凤凰家园”项目正式开工,标志着南昌当年70万平方米的经济适用房建设的全面启动。凤凰家园位于南昌市丰和
摘要:在传统的小学教学理念当中,老师就是信息和知识的传播者。但现如今,随着科学技术的不断发展,一些新的媒体技术不断引入教学当中,尽管小学信息技术的教学难度并不大,但在科技发展的推动之下,如何利用这些新的科学技术推动信息技术课堂更好的开展教学任务,帮助学生理解和掌握学习内容,已然成为信息技术课堂老师极为关注的一点。随着翻转课堂在全国的不断兴起,这种教学任务也成为信息技术课堂教改任务之一。  关键词:
富丽华德新动力是诺贝尔奖得主弗里德·穆拉德(Dr FerldMurad)博士及其科研团队30余年来对一氧化氮的研究成果。富丽华德新动力精选大自然中多种植物精华,采取最先进的纳米级
不久前,第47届希腊萨洛尼基国际电影节主席戴斯皮娜·莫萨基特邀徐静蕾担任影展评委,同时,还专门为她的三部导演作品《我和爸爸》、《一封陌生女人的来信》、《梦想照进现实》做主题放映。此外,由她主演的另外两部影片《开往春天的地铁》和《我爱你》还在“中国新电影:另一种视角”单元中展映。  与此同时,由刘伟强、麦兆辉执导,徐静蕾和梁朝伟、金城武、舒淇共同打造的《伤城》也于贺岁档期上映。对于有记者问她是否担心
摘要:为了获取SA06铝合金板材不同温度及应变率条件下本构模型及韧性断裂性能,对SA06铝合金板材进行了热态单向拉伸试验,结合热态单向拉伸试验和韧性断裂试验结果,提出了一种修
期刊