企图把人麻风病转移到热血动物或冷血动物体内的实验,已做过很多,直至1960年夏普氏的小白鼠足垫接种才获得麻风菌的繁殖。Rees 和 Water 随即试用免疫抑制方法,把这种局部有限的繁殖变成全身性感染。Fiedsteel 和 Mc Intosh 进而试用胸腺摘除的新生路易斯鼠。其后 Kohsaka、Mori、Ito、Nakamura、Yogi 和 Colstan 氏等,更用先天性无胸腺的裸鼠做实验。正常小鼠仍然是重要的实验动物之一,它结合生化试验以鉴定麻风分支杆菌。最近,在印度南部,小白鼠足垫技术已经用于节足动物传播麻风的实验。Kazda、Irgens 和 There have been many attempts to transfer human leprosy to warm-blooded or cold-blooded animals until Jatropha’s footpad inoculation in 1960 was successful. Rees and Water went on to try immunosuppressive methods to turn this locally limited reproduction into a systemic infection. Fiedsteel and Mc Intosh went on to try the thymus removal of newborn Lewis rats. Later, Kohsaka, Mori, Ito, Nakamura, Yogi and Colstan’s and so on, but with congenital athymic nude mice experiment. Normal mice are still one of the important experimental animals that combine biochemical tests to identify M. leprae. Recently, mouse footpad technology has been used in experiments in leprosy animals in southern India. Kazda, Irgens and