男患,22岁。动作迟缓,走路不稳5年,四肢不自主抖动,双膝弯屈费力,构音障碍,流涎,反应迟钝。常独自发呆、发笑1年。无肝炎、癫痫、脑炎等病史。3个月前来我院治疗。门诊查体:神志清,颈软,角膜K-F环明显。双眼球水平震颤,瞳孔及眼底正常,四肢震颤,肌张力增高,肌力及感觉正常。无病理反射。血清铜蓝白21mg/L(正常250～400mg/L),血清铜氧化酶活性0.02 OD(正常0.2～5.3 Male suffering, 22 years old. Slow movements, walking unsteady for 5 years, limbs involuntary jitter, knees buckling effort, dysarthria, salivation, unresponsive. Often alone daze, laughing for 1 year. No hepatitis, epilepsy, encephalitis and other medical history. 3 months ago to our hospital for treatment. Outpatient examination: conscious, soft neck, corneal K-F ring significantly. Both eyes tremor tremor, pupil and fundus normal limb tremor, increased muscle tone, muscle strength and sense of normal. No pathological reflex. Serum copper blue and white 21mg / L (normal 250 ~ 400mg / L), serum copper oxidase activity 0.02 OD (normal 0.2 ~ 5.3